Given the current shortage of Dextrose 50%, cases of hypoglycemia can be treated as per a standing order with Dextrose 10%.

For a hypoglycemic emergency, the standard initial dose of dextrose is 12.5 mg.

This would be “half an amp of D50” or 25 mLs from a standard 50 mL ampule of 50% Dextrose.

The 12.5 mg dose, if given in 10% Dextrose equivalents, would be 125 mL.

Whether giving dextrose as 50% or 10% solutions, a second dose of 12.5 mg of dextrose is allowed per protocol for persistent hypoglycemia and altered mental status.