Depression: What Is It?Depression is a word commonly used to describe an overwhelming weariness or sadness about life—a feeling of physical and emotional fatigue that goes beyond the normal reactions to loss, failure or disappointment. Life events sometimes trigger sadness or depression that fades with time and emotional healing. But clinical depression is depression that lasts longer than a few weeks or interferes with the ability to participate in everyday life. Clinical depression isn't just a "negative attitude" or "the blues." It is an illness resulting from complex interactions between brain chemicals, hormones and other factors.
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